Anti-Calponin 1 antibodies are used for the immunodetection of the protein encoded by the CNN1 gene. In humans, the canonical protein has a reported length of 297 amino acid residues and a mass of 33.2 kDa. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Calponin protein family, it is known to be involved with muscle contraction.
The calponin 1 marker can be used to characterize Vascular Smooth Muscle Cells, Bronchus Submucosal Gland Myoepithelial Cells, Bronchial Smooth Muscle Cells, Tracheobronchial Smooth Muscle Cells, and Bronchiolar Smooth Muscle Cells.* Other names for this target antigen include SMCC, Sm-Calp, basic calponin, calponin 1, basic, smooth muscle, calponin H1, smooth muscle, and HEL-S-14. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. Over 310 citations in the literature describe the use of Calponin 1 antibodies in research. Immunohistochemistry is a widely used application for these antibodies. Flow Cytometry, Western Blot, Immunocytochemistry, and Immunofluorescence are also common applications.
*HuBMAP Human Reference Atlas v1.4